CHEMBL471880


SMILES CCCCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4cc(Cl)ccc43)CC2)C1=O
InChIKey GCQBOMHBVPHVMB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 522.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.22 9.22 9.22 ChEMBL
δ OPRD Human Opioid A pKi 6.05 6.05 6.05 ChEMBL
κ OPRK Human Opioid A pKi 7.6 7.6 7.6 ChEMBL
μ OPRM Human Opioid A pKi 7.3 7.3 7.3 ChEMBL
NOP OPRX Human Opioid A pKi 9.22 9.22 9.22 PDSP Ki database
δ OPRD Human Opioid A pKi 6.05 6.05 6.05 PDSP Ki database
κ OPRK Human Opioid A pKi 7.6 7.6 7.6 PDSP Ki database
μ OPRM Human Opioid A pKi 7.3 7.3 7.3 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database