CHEMBL473272


SMILES CCCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey UYKIELXFWCAQSU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 474.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.0 9.0 9.0 ChEMBL
δ OPRD Human Opioid A pKi 5.63 5.63 5.63 ChEMBL
κ OPRK Human Opioid A pKi 7.35 7.35 7.35 ChEMBL
μ OPRM Human Opioid A pKi 7.37 7.37 7.37 ChEMBL
NOP OPRX Human Opioid A pKi 9.0 9.0 9.0 PDSP Ki database
δ OPRD Human Opioid A pKi 5.63 5.63 5.63 PDSP Ki database
κ OPRK Human Opioid A pKi 7.35 7.35 7.35 PDSP Ki database
μ OPRM Human Opioid A pKi 7.37 7.37 7.37 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database