CHEMBL473699


SMILES Cc1nc2cc3c(cc2[nH]1)[C@@]1(C)CCN(CC2CC2)C(C3)[C@@H]1C
InChIKey PVOGJENIZFDIAO-BFKPJKFSSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.75 7.75 7.75 ChEMBL
κ OPRK Human Opioid A pKi 10.3 10.3 10.3 ChEMBL
μ OPRM Human Opioid A pKi 9.11 9.11 9.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.24 8.24 8.24 ChEMBL
μ OPRM Human Opioid A pEC50 7.75 7.75 7.75 ChEMBL
μ OPRM Human Opioid A pIC50 4.96 4.96 4.96 ChEMBL