CHEMBL474485


SMILES CNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey IDXQXXMUKWSUCZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 446.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.68 8.68 8.68 ChEMBL
δ OPRD Human Opioid A pKi 5.89 5.89 5.89 ChEMBL
κ OPRK Human Opioid A pKi 7.32 7.32 7.32 ChEMBL
μ OPRM Human Opioid A pKi 7.46 7.46 7.46 ChEMBL
NOP OPRX Human Opioid A pKi 8.68 8.68 8.68 PDSP Ki database
δ OPRD Human Opioid A pKi 5.89 5.89 5.89 PDSP Ki database
κ OPRK Human Opioid A pKi 7.32 7.32 7.32 PDSP Ki database
μ OPRM Human Opioid A pKi 7.46 7.46 7.46 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database