CHEMBL4745486


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](C)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O
InChIKey IMAPHLUZSKKZIP-AUSZWPCGSA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 15
Rotatable bonds 31
Molecular weight (Da) 1006.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.44 6.44 6.44 ChEMBL
κ OPRK Human Opioid A pKi 7.03 7.03 7.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 6.14 6.14 6.14 ChEMBL
κ OPRK Human Opioid A pIC50 6.12 6.51 6.9 ChEMBL