CHEMBL474708


SMILES C#CCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O
InChIKey BCFWMJUOTGHXSO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.63 6.63 6.63 ChEMBL
δ OPRD Human Opioid A pKi 4.36 4.36 4.36 ChEMBL
κ OPRK Human Opioid A pKi 5.9 5.9 5.9 ChEMBL
μ OPRM Human Opioid A pKi 5.37 5.37 5.37 ChEMBL
NOP OPRX Human Opioid A pKi 6.63 6.63 6.63 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Human Opioid A pKi 5.9 5.9 5.9 PDSP Ki database
μ OPRM Human Opioid A pKi 5.37 5.37 5.37 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database