CHEMBL4747929


SMILES COc1nc(-c2ncco2)nc(N)c1C(=O)NCc1c(Cl)cccc1Cl
InChIKey MZALOVKMJUTVDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 393.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKi 8.27 8.27 8.27 ChEMBL
A2A AA2AR Human Adenosine A pKi 10.11 10.11 10.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Human Adenosine A pIC50 7.77 7.77 7.77 ChEMBL