CHEMBL475096


SMILES CCNCCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)C1=O
InChIKey SZEZVGVHEGRAQG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 536.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.06 6.06 6.06 ChEMBL
κ OPRK Human Opioid A pKi 6.3 6.3 6.3 ChEMBL
μ OPRM Human Opioid A pKi 6.11 6.11 6.11 ChEMBL
δ OPRD Human Opioid A pKi 6.06 6.06 6.06 PDSP Ki database
κ OPRK Human Opioid A pKi 6.3 6.3 6.3 PDSP Ki database
μ OPRM Human Opioid A pKi 6.11 6.11 6.11 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.68 8.68 8.68 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database