CHEMBL477154


SMILES Cn1c2c(c3ccccc31)C[C@@]1(O)[C@H]3Cc4ccc(O)c5c4[C@@]1(CCN3CC1CC1)[C@H]2O5
InChIKey CRTCCMARDBQOKA-NVSKSXHLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 428.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.19 7.49 8.08 ChEMBL
δ OPRD Human Opioid A pKi 9.31 10.0 10.7 ChEMBL
κ OPRK Human Opioid A pKi 8.08 8.08 8.08 ChEMBL
μ OPRM Human Opioid A pKi 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database