CHEMBL477650


SMILES CC1=C(CCN(C)C)c2cc(NS(=O)(=O)c3csc4ccccc34)ccc2C1
InChIKey XWXCMQFSARGQNK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 412.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pIC50 6.16 6.16 6.16 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 9.52 9.52 9.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.94 5.94 5.94 ChEMBL