CHEMBL4797325


SMILES O=C(Nc1nc(-c2ccccc2)c(C(=O)c2ccc(F)cc2F)s1)c1ccco1
InChIKey RVXUCDYZOPPLSL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 410.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 7.13 7.13 7.13 ChEMBL
A1 AA1R Rat Adenosine A pKi 8.18 8.18 8.18 ChEMBL
A3 AA3R Human Adenosine A pKi 6.91 6.91 6.91 ChEMBL
A2A AA2AR Human Adenosine A pKi 6.88 6.88 6.88 ChEMBL
A1 AA1R Human Adenosine A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database