CHEMBL484357


SMILES CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CC=C(C#Cc2ccccc2)CC1
InChIKey YDCWHOYYMICCQD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 490.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.52 6.52 6.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.26 5.29 5.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.26 5.29 5.33 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.52 6.52 6.52 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.51 5.51 5.51 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.51 5.51 5.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database