CHEMBL4846243


SMILES C/C=C1/CN2CC[C@@]34c5ccccc5N(C)[C@]35OC[C@@]4(C(=O)OC)[C@H]1C[C@H]25
InChIKey HAGBWVNSVWLTKY-ZFWLQQAWSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 5.08 5.09 5.1 ChEMBL
κ OPRK Human Opioid A pKi 5.6 5.62 5.65 ChEMBL
μ OPRM Human Opioid A pKi 6.2 6.28 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pIC50 5.19 5.2 5.2 ChEMBL
μ OPRM Mouse Opioid A pIC50 5.28 5.29 5.3 ChEMBL
μ OPRM Mouse Opioid A pEC50 5.28 5.29 5.3 ChEMBL
δ OPRD Mouse Opioid A pIC50 4.02 4.02 4.02 ChEMBL