CHEMBL4849230


SMILES CN1CCN(c2nc(N)nc(CCCOc3cc(Cl)ccc3Cl)n2)CC1
InChIKey OAYFFKDPUNMJMP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 396.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.1 5.1 5.1 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.84 6.08 6.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database