CHEMBL4858567


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)Nc1ccccc1
InChIKey JAGDPXWZXXDZGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 332.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 4.65 4.65 4.65 ChEMBL
H2 HRH2 Human Histamine A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 5.47 5.88 6.28 ChEMBL