CHEMBL4861311


SMILES Fc1ccc2c(C3CCN(CCCOc4ccc(CCN5CCCCC5)cc4)CC3)noc2c1
InChIKey WAIZFEIVFOBJJX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 465.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.99 5.99 5.99 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.27 6.27 6.27 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
H3 HRH3 Human Histamine A pKi 7.87 7.87 7.87 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.12 6.12 6.12 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.03 8.03 8.03 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.13 8.13 8.13 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.01 8.01 8.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database