CHEMBL4861794


SMILES Nc1ccc(C(=O)CCCN2CCN(c3ccccn3)CC2)cc1
InChIKey JPLZGZBACZPXMR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 324.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.56 6.61 6.65 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.46 7.48 7.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.33 6.33 6.33 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.75 6.78 6.81 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database