CHEMBL4871880


SMILES C/C=C1/CN2CC[C@@]34c5cc(O)ccc5N(C)[C@]35OC[C@@]4(C(=O)OC)[C@H]1C[C@H]25
InChIKey YILKZADAWNUTTB-QLWRWLBVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 382.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 4.98 4.99 5.0 ChEMBL
κ OPRK Human Opioid A pKi 5.78 5.79 5.8 ChEMBL
μ OPRM Human Opioid A pKi 6.5 6.51 6.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pIC50 7.14 7.14 7.14 ChEMBL
μ OPRM Mouse Opioid A pIC50 5.58 5.59 5.6 ChEMBL
μ OPRM Mouse Opioid A pEC50 5.58 5.59 5.6 ChEMBL
δ OPRD Mouse Opioid A pIC50 4.69 4.7 4.7 ChEMBL