CHEMBL4876193


SMILES Cc1cccc(-c2n[nH]cc2N2CCCNCC2)c1
InChIKey DZSVIKVOAPBNLM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 256.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.48 5.48 5.48 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.91 7.92 7.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.44 5.44 5.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.13 5.55 5.98 ChEMBL