CHEMBL1277105


SMILES O=S(=O)(c1cccc2ccccc12)c1n[nH]c2ccc(N3CCNCC3)cc12
InChIKey FYOVZCDHYOEKDE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 392.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.81 5.81 5.81 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.89 7.89 7.89 ChEMBL