CHEMBL490644


SMILES O=C1Cc2ccccc2N1C/C=C\CN1CCN(c2cccc3ccccc23)CC1
InChIKey GIFYHUSNALLKOZ-WAYWQWQTSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 397.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.94 7.94 7.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database