CHEMBL493266


SMILES CCC(=O)c1cccc(C(=O)NCc2ccc(F)c(-c3cccc(CN4CCN[C@@H](C)C4)c3)c2)c1
InChIKey NAOXUXMOYDUMFJ-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 473.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 10.3 10.3 10.3 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 7.6 7.6 7.6 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKd 9.0 9.0 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database