chemerin C-terminal peptide


SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)O
InChIKey QLVGSBXIQFERFK-NBBYSTNSSA-N
Sequence YFPGQFAFS

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 12
Rotatable bonds 28
Molecular weight (Da) 1062.5

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 8JJP 7YKD 8SG1

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
chemerin CML1 Human Chemerin receptor A pKd 7.62 7.88 8.15 Guide to Pharmacology
chemerin CML1 Human Chemerin receptor A pKi 7.72 7.72 7.72 ChEMBL
chemerin 2 CML2 Human Chemerin receptor A pKi 7.45 7.77 8.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
chemerin 2 CML2 Human Chemerin receptor A pEC50 9.0 9.0 9.0 Guide to Pharmacology
chemerin CML1 Human Chemerin receptor A pEC50 6.87 7.45 8.05 ChEMBL