CHEMBL495097


SMILES CC(Oc1ccccc1/C=N/OCc1ccccc1)C1=NCCN1
InChIKey KUWSYGHOSHDWCB-LPYMAVHISA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 323.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.06 6.06 6.06 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.17 6.17 6.17 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.67 6.67 6.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 4.5 4.5 4.5 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 5.45 5.45 5.45 ChEMBL