CHEMBL497604


SMILES N#Cc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4o3)CC2)c1
InChIKey AFUIBDRITZEBAF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.07 6.07 6.07 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.06 6.06 6.06 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.27 9.27 9.27 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.06 6.06 6.06 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 9.27 9.27 9.27 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database