CHEMBL498311


SMILES CCC(CC)c1cc(C)nn2c(-c3sc(N4CCOCC4)nc3Cl)c(C)nc12
InChIKey PHKJVUUMSPASRG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF2 CRFR2 Human Corticotropin-releasing factor B1 pKi 4.77 4.77 4.77 ChEMBL
CRF1 CRFR1 Human Corticotropin-releasing factor B1 pKi 8.0 9.13 9.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database