CHEMBL501088


SMILES O=C1N(CCNCC2CCCCC2)CN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey AQGQQVZAISJFLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 604.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.42 8.42 8.42 ChEMBL
δ OPRD Human Opioid A pKi 5.81 5.81 5.81 ChEMBL
κ OPRK Human Opioid A pKi 6.57 6.57 6.57 ChEMBL
μ OPRM Human Opioid A pKi 5.75 5.75 5.75 ChEMBL
NOP OPRX Human Opioid A pKi 8.42 8.42 8.42 PDSP Ki database
κ OPRK Human Opioid A pKi 6.57 6.57 6.57 PDSP Ki database
μ OPRM Human Opioid A pKi 5.74 5.74 5.74 PDSP Ki database
δ OPRD Human Opioid A pKi 5.81 5.81 5.81 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database