CHEMBL5028466


SMILES CC(=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)N[C@H](CCCN)C(=O)NCCN1CCN(CCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey AGVQGHLXLYNMSL-BOALQFNTSA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 10
Rotatable bonds 24
Molecular weight (Da) 930.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.21 6.21 6.21 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.19 6.19 6.19 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.73 9.73 9.73 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.09 8.09 8.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database