CHEMBL506272


SMILES CCC[C@H]1C(=O)N([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)C1CCC(=O)N1
InChIKey NSBYFZXDVSHNEF-WDSZSSPESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 629.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 6.44 6.44 6.44 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.89 6.89 6.89 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 6.98 6.98 6.98 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 7.6 7.6 7.6 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.7 8.7 8.7 ChEMBL