CHEMBL510201


SMILES CN1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O
InChIKey KXTDPQYMFXDMPR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.51 7.51 7.51 ChEMBL
δ OPRD Human Opioid A pKi 4.48 4.48 4.48 ChEMBL
κ OPRK Human Opioid A pKi 6.82 6.82 6.82 ChEMBL
μ OPRM Human Opioid A pKi 6.16 6.16 6.16 ChEMBL
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Human Opioid A pKi 6.82 6.82 6.82 PDSP Ki database
μ OPRM Human Opioid A pKi 6.16 6.16 6.16 PDSP Ki database
NOP OPRX Human Opioid A pKi 7.51 7.51 7.51 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database