CHEMBL512150


SMILES NC(=O)c1ccc2c(c1O)[C@]13CCN(CC4CCC4)[C@H](C2)[C@]1(O)CC[C@H](O)C3
InChIKey NWIALXFYKPFWTR-VYOKXSSZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.11 7.11 7.11 ChEMBL
κ OPRK Human Opioid A pKi 8.05 8.05 8.05 ChEMBL
μ OPRM Human Opioid A pKi 9.23 9.25 9.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.41 8.41 8.41 ChEMBL
μ OPRM Human Opioid A pEC50 8.51 8.53 8.55 ChEMBL
μ OPRM Human Opioid A pIC50 7.33 7.46 7.58 ChEMBL