CHEMBL516024


SMILES COCCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)C1=O
InChIKey NAEXFKGFHAXVRU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 523.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 4.54 4.54 4.54 ChEMBL
κ OPRK Human Opioid A pKi 5.74 5.74 5.74 ChEMBL
μ OPRM Human Opioid A pKi 6.14 6.14 6.14 ChEMBL
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
NOP OPRX Human Opioid A pKi 7.59 7.59 7.59 PDSP Ki database
κ OPRK Human Opioid A pKi 5.74 5.74 5.74 PDSP Ki database
μ OPRM Human Opioid A pKi 6.14 6.14 6.14 PDSP Ki database
NOP OPRX Human Opioid A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database