CHEMBL5172639


SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C/C=C(\F)[C@@H](N)Cc1ccc(O)cc1)C(=O)NC1CC1
InChIKey GXSYRAHYTOZOPD-DQKXXYJSSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 6
Rotatable bonds 16
Molecular weight (Da) 595.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.99 6.99 6.99 ChEMBL
μ OPRM Human Opioid A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 6.9 6.9 6.9 ChEMBL
δ OPRD Mouse Opioid A pIC50 6.82 6.82 6.82 ChEMBL
δ OPRD Human Opioid A pEC50 6.16 6.16 6.16 ChEMBL
μ OPRM Human Opioid A pEC50 5.37 5.37 5.37 ChEMBL