CHEMBL517407


SMILES CN(CC/C=C1\c2ccccc2Sc2ccc(Cl)cc21)Cc1ccc(OCCCN2CCCCC2)cc1
InChIKey DSRXHDAICZGTCK-ORBVJSQLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 532.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.53 6.53 6.53 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.61 6.61 6.61 ChEMBL
H3 HRH3 Human Histamine A pKi 8.81 8.81 8.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.3 7.3 7.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.28 7.28 7.28 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.53 6.53 6.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database