CHEMBL5175717


SMILES O=C(Cc1ccccc1)N[C@H]1C[C@]23CCN(CC4CC4)[C@H](Cc4ccc(O)cc42)[C@]32CC[C@@H]1O2
InChIKey OHPZSCSFNDIFCZ-NCPANSIKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 458.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.3 8.3 8.3 ChEMBL
κ OPRK Human Opioid A pKi 8.77 8.77 8.77 ChEMBL
μ OPRM Human Opioid A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.42 8.42 8.42 ChEMBL
κ OPRK Human Opioid A pEC50 7.87 7.87 7.87 ChEMBL
μ OPRM Human Opioid A pEC50 8.27 8.27 8.27 ChEMBL