CHEMBL5177001


SMILES CCC(=O)N(c1ccccc1)C1CCN(C(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)C/C=C(\F)[C@@H](N)Cc2ccc(O)cc2)CC1
InChIKey UJVAKTSNKRZVJI-XRELOVPQSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 14
Molecular weight (Da) 657.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.43 6.43 6.43 ChEMBL
μ OPRM Human Opioid A pKi 6.43 6.43 6.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 6.74 6.74 6.74 ChEMBL
δ OPRD Mouse Opioid A pIC50 6.87 6.87 6.87 ChEMBL
δ OPRD Human Opioid A pEC50 5.41 5.41 5.41 ChEMBL