CHEMBL5189520


SMILES COc1ccccc1OCCNc1nc(N)nc(NCCc2c[nH]c3ccccc23)n1
InChIKey XNPKKTJJUINFAT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 10
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.89 4.89 4.89 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.36 5.36 5.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database