CHEMBL5192115


SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C/C=C(\F)[C@@H](N)Cc1ccc(O)cc1)C(N)=O
InChIKey JRQWLWZTKLOPSQ-ICXILOJFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 6
Rotatable bonds 15
Molecular weight (Da) 555.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.03 7.03 7.03 ChEMBL
μ OPRM Human Opioid A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 6.73 6.73 6.73 ChEMBL
δ OPRD Mouse Opioid A pIC50 7.33 7.33 7.33 ChEMBL
δ OPRD Human Opioid A pEC50 6.02 6.02 6.02 ChEMBL
μ OPRM Human Opioid A pEC50 5.58 5.58 5.58 ChEMBL