CHEMBL5197911


SMILES COc1ccccc1N1CCN(CCCCCCNc2nc(N)nc(N)n2)CC1
InChIKey LXKSIEBMEPDEFX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 400.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.15 6.15 6.15 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.11 5.11 5.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.84 5.84 5.84 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database