CHEMBL5198168


SMILES CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C/C=C(\F)[C@@H](N)Cc1ccc(O)cc1
InChIKey FWDJGOHQYSBTRO-GUOSAUPISA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 6
Rotatable bonds 16
Molecular weight (Da) 583.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.26 7.26 7.26 ChEMBL
μ OPRM Human Opioid A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 6.75 6.75 6.75 ChEMBL
δ OPRD Mouse Opioid A pIC50 7.18 7.18 7.18 ChEMBL
δ OPRD Human Opioid A pEC50 6.16 6.16 6.16 ChEMBL
μ OPRM Human Opioid A pEC50 5.64 5.64 5.65 ChEMBL