CHEMBL5203813


SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C/C=C(\F)[C@@H](N)Cc1ccc(O)cc1)C(=O)N(C)C
InChIKey SFVRUVTYOGSOAR-GUOSAUPISA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 5
Rotatable bonds 15
Molecular weight (Da) 583.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.59 6.59 6.59 ChEMBL
μ OPRM Human Opioid A pKi 7.07 7.07 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 6.0 6.0 6.0 ChEMBL
δ OPRD Mouse Opioid A pIC50 6.37 6.37 6.37 ChEMBL
δ OPRD Human Opioid A pEC50 5.42 5.42 5.42 ChEMBL
μ OPRM Human Opioid A pEC50 4.75 4.75 4.75 ChEMBL