CHEMBL5204274


SMILES O=C(NCCCCCCn1nc2ccccn2c1=O)N1CCN(c2cccc(Cl)c2)CC1
InChIKey LQACCULQLKHGMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 456.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.59 5.59 5.59 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.71 5.71 5.71 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database