CHEMBL52096


SMILES Cc1cc(=O)oc2cc(OCCCN3CCN(c4ccccc4)CC3)ccc12
InChIKey ZYBLSQVXWVJACW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Rat Adrenoceptors A pKd 7.93 7.93 7.93 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.13 7.42 7.72 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.86 7.92 7.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database