CHEMBL5279890


SMILES CN(C)C[C@@H]1CN(C(=O)Cc2cc(F)c(F)cc2F)CC[C@@]1(O)c1cccc(O)c1
InChIKey JMDFENKDWRFUQU-OPAMFIHVSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 8.74 8.74 8.74 ChEMBL
δ OPRD Human Opioid A pKi 6.75 6.75 6.75 ChEMBL
κ OPRK Human Opioid A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 6.87 6.87 6.87 ChEMBL
κ OPRK Human Opioid A pEC50 5.99 5.99 5.99 ChEMBL
μ OPRM Human Opioid A pEC50 7.73 7.73 7.73 ChEMBL