CHEMBL5287134


SMILES CN(C)C[C@H]1CN(C(=O)Cc2cc(F)c(F)cc2F)CC[C@]1(O)c1cccc(O)c1
InChIKey JMDFENKDWRFUQU-AOMKIAJQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 7.27 7.27 7.27 ChEMBL
δ OPRD Human Opioid A pKi 5.45 5.45 5.45 ChEMBL
κ OPRK Human Opioid A pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 6.3 6.3 6.3 ChEMBL
μ OPRM Human Opioid A pEC50 6.96 6.96 6.96 ChEMBL