CHEMBL5287792


SMILES CN(C)CC1CN(C(=O)CCc2cccc(C(F)(F)F)c2)CCC1(O)c1cccc(O)c1
InChIKey BTTDVYVTDTUALJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.1 8.1 8.1 ChEMBL
κ OPRK Human Opioid A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.84 7.84 7.84 ChEMBL
κ OPRK Human Opioid A pEC50 6.98 6.98 6.98 ChEMBL
μ OPRM Human Opioid A pEC50 8.55 8.55 8.55 ChEMBL