CHEMBL5289083


SMILES CN1/C(=C/C=C/C=C/C2=[N+](CCCCCC(=O)NCCCNCCCCCCN3CCC(COC(=O)Nc4ccc(F)cc4-c4ccc(F)c(Cl)c4)CC3)c3ccccc3C2(C)C)C(C)(C)c2ccccc21
InChIKey POIIDLJXIAHDFT-UHFFFAOYSA-O

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 24
Molecular weight (Da) 1001.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.75 7.75 7.75 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.77 8.77 8.77 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.0 8.0 8.0 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.72 8.72 8.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database