CHEMBL5290432


SMILES C/C=C1\CN2CC[C@@]34c5ccccc5N(CCc5ccccc5)[C@]35OC[C@@]4(C(=O)OC)[C@H]1C[C@H]25
InChIKey MDHIFDZZMWLNKL-WZOWOQAZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 456.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 6.2 6.22 6.24 ChEMBL
μ OPRM Human Opioid A pKi 7.9 7.91 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pEC50 6.13 6.13 6.13 ChEMBL
μ OPRM Mouse Opioid A pEC50 7.1 7.11 7.12 ChEMBL
δ OPRD Human Opioid A pEC50 6.21 6.21 6.21 ChEMBL