CHEMBL5315170


SMILES CCCC(=O)NCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O
InChIKey VVYQHHROMNFSAO-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 466.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.1 7.1 7.1 ChEMBL
H1 HRH1 Human Histamine A pKi 9.1 9.1 9.1 ChEMBL
H1 HRH1 Human Histamine A pKd 9.2 9.2 9.2 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database