CHEMBL53294


SMILES CCCN1CCc2cc(OC)cc3c2[C@H]1Cc1ccc(O)c(O)c1-3
InChIKey WNNMRMNAGNMVEW-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 325.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.19 5.56 5.75 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.09 8.56 9.77 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.09 8.09 8.09 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.99 8.99 8.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 5.48 5.48 5.48 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.99 8.49 8.99 ChEMBL